March 18, 2011 in Technology (F)
[prMac.com] Cambridge, United Kingdom - MacVector, Inc has just released MacVector 12.0 a major update with many new and enhanced features that further simplifies DNA and protein sequence analysis for all molecular biologists. In line with MacVector, Inc's policy of maintaining close relationships with users, MacVector 12 includes many feature requests from the 2010 user survey as well as makes the interface more accessible to new users.
Specific changes include Click Cloning enhancements, which have removed the guesswork of selecting suitable restriction sites for clone construction. A new graphical map has improved navigation features with multiple selection modes and the ability to seamlessly zoom in and out of both circular and linear sequences using either mouse or keyboard. The Editor now has the ability to use mixed case residues in the editor and colors to emphasize regions or features of interest. MacVector is now fully circular sequence aware and has the ability to design PCR primers and select features for analysis across the circular origin.
With these new features and changes from the last few releases, MacVector strengths are:
* Ease of use, with all functions a mouse click away from the sequence window.
* Visualizing feature rich annotated sequences with a sequence overview allowing users to see their full sequence at a glance.
* Subcloning: A very simple point and click interface allows you to select restriction enzyme sites, digest, then ligate into a vector with a minimum of steps. Compatible sites are highlighted to simplify the choices with a tool to modify overhanging ends if required. MacVector also supports Gateway and TOPO cloning.
* Comparing sequences: You can align cDNA/mRNA/EST clones against genomic sequences. Run Blast searches with your sequence, search and align against multiple sequences on your hard drive and generate publication ready dot plots.
* Opening data from many sources: MacVector will import sequences direct from the NCBI's Entrez database, from Vector NTI databases, from text files in many formats (e.g. GenBank, EMBL, GCG etc) or from sequencing facility files in Fastq, ABI or SCF formats.
* A wide array of algorithms, combined with drag and drop of results to parental sequences, makes it a quick process to annotate blank sequences with features, ready to use in the lab.
MacVector, Inc's President, Dr. Kevin Kendall, said "While other applications add features you will never use, MacVector strives to improve the functions you use everyday to make this the most intuitive and practical application you will ever need for editing, analyzing and documenting DNA and protein sequences. Visualizing a graphical map with the new sequence overview simplifies the interface so that even very large sequences with a rich level of annotation can be visualized and navigated easily. When you need to get down to the sequence residue level to see translations of individual coding region, MacVector 12 lets you do both in the same window."
* Mac OS X 10.4 or above
Price and Availability:
Bulk product pricing is available for MacVector 12.0 from the MacVector website.
MacVector, Inc. was formed at the beginning of 2007 to develop, support and sell MacVector and Assembler. An easy to use sequence analysis application for molecular biologists. MacVector has offices in the US and the UK, along with distributors in Japan, Taiwan and Australia. Copyright (C) 2011 MacVector, Inc. All Rights Reserved. Apple, the Apple logo, iPhone, iPod and iPad are registered trademarks of Apple Inc. in the U.S. and/or other countries.